Advise patients of the chance of lifestyle-threatening respiratory despair, including information that the risk is greatest when starting off OXYCONTIN or once the dosage is elevated, and that it might manifest even at proposed dosages.
Keep away from having grapefruit or ingesting grapefruit juice although making use of this medication Unless of course your health practitioner or pharmacist claims you may accomplish that safely and securely. Grapefruit can increase the possibility of Unwanted effects with this medicine. Question your medical professional or pharmacist For additional specifics.
People who practical experience breakthrough suffering might demand a dosage adjustment of OXYCONTIN or might require rescue medication with an appropriate dose of a right away-release analgesic.
The concomitant use of anticholinergic drugs may well increase chance of urinary retention and/or extreme constipation, which can lead to paralytic ileus.
Supportive steps (together with oxygen and vasopressors) needs to be employed during the administration of circulatory shock and pulmonary edema accompanying overdose as indicated. Cardiac arrest or arrhythmias may perhaps need cardiac massage or defibrillation.
Make certain you understand how to get oxycodone and what other drugs you should steer clear of having with it. See also Drug Interactions area. Get health-related help at once if any here of such really major side effects manifest: sluggish/shallow breathing, strange lightheadedness, intense drowsiness/dizziness, problem waking up.
The dosage relies on your own health care situation and response to therapy. Tend not more info to enhance your dose, go ahead and take medication far more usually, or get it for a longer time read more than prescribed. Effectively quit the medication when so directed.
Using OXYCONTIN in individuals with acute or extreme bronchial bronchial asthma within an unmonitored environment or while in the absence of resuscitative equipment is contraindicated.
Dispose of expired, undesired, or unused OXYCONTIN by instantly flushing down the toilet, if a drug get-again option isn't readily available. Visit for additional information on disposal of unused medicines.
When you've got nausea, it could aid to just take this drug with foodstuff. Check with your medical professional or pharmacist about other tips on how to lessen nausea (including lying down for 1 to two hours with as very website little head movement as is possible). If nausea lasts, see your medical professional.
Prolonged usage of OXYCONTIN in the course of pregnancy may result in neonatal opioid withdrawal syndrome, which may be lifetime-threatening Otherwise recognized and treated, and involves administration Based on protocols formulated by neonatology experts.
There won't be any conventional opioid tapering schedules which might be suited to all individuals. Excellent medical apply dictates a affected individual-precise decide to taper the dose in the opioid steadily. For people on OXYCONTIN who click here are bodily opioid-dependent, initiate the taper by a small enough increment (e.
To reduce the potential risk of dizziness and lightheadedness, rise up slowly when rising from a sitting down or lying place.
Phase #2: If rounding is necessary, often round the dosage right down to the closest OXYCONTIN tablet strength offered and initiate OXYCONTIN therapy with that dose.